FRTRUST: a fuzzy reputation based model for trust management in semantic P2P grids

Grid and peer-to-peer (P2P) networks are two ideal technologies for file sharing. A P2P grid is a special case of grid networks in which P2P communications are used for communication between nodes and trust management. Use of this technology allows creation of a network with greater distribution and scalability. Semantic grids have appeared as an expansion of grid networks in which rich resource metadata are revealed and clearly handled. In a semantic P2P grid, nodes are clustered into different groups based on the semantic similarities between their services. This paper proposes a reputation model for trust management in a semantic P2P Grid. We use fuzzy theory, in a trust overlay network named FR TRUST that models the network structure and the storage of reputation information. In fact we present a reputation collection and computation system for semantic P2P Grids. The system uses fuzzy theory to compute a peer trust level, which can be either: Low, Medium, or High. Our experimental results demonstrate that FR TRUST combines low (and therefore desirable) a good computational complexity with high ranking accuracy.Comment: 12 Pages, 10 Figures, 3 Tables, InderScience, International Journal of Grid and Utility Computin

Effects of the Municipal Solid Waste Landfill on the Quality of Water Resources in Khalkhal: A Case Study

Transmission of leachate from municipal solid waste landfills can potentially threaten ecosystems and human societies when the landfill has no system for collecting and treating leachate. Leachate produced from landfills finds its way through the soil to groundwater and surrounding surface waters, leading to pollution of water resources. This study aimed to investigate the effects of leachate from Khalkhal landfill (a city in Ardabil province, northwestern Iran) on the quality of groundwater and surrounding surface water. During 2019-2020, 4 wells (one control well located upstream of the landfill and three wells located downstream of the landfill) and two stations of the surface water resource of the Herochai river were spots for sampling. First, we did sampling during high and low rainfall seasons in accordance with the standards. Second, we analyzed the values of some physical, chemical, and biological quality parameters according to standard methods. The sampling of the soil texture was conducted following ASTM D 422 standards. Then, the soil was analyzed at Reference Laboratory of Water, Soil, and Plant in Ardabil province. The value of most parameters measured in the water of downstream wells was lower than the limit recommended by the Iranian and World Health Organization, indicating no limitation for drinking and agricultural uses. The quality of the Herochai river water was also relatively undesirable in terms of turbidity and total coliform in some samples. Additionally, consistent with the study results, no difference was observed between high and low rainfall seasons. According to the results obtained from different parameters, Schuler and Wilcox diagrams, and landfill water pollution index (LWPI), the quality of upstream and downstream water resources of Khalkhal municipal solid waste landfill was not much different. In other words, the landfill did not affect water

The unfinished agenda of communicable diseases among children and adolescents before the COVID-19 pandemic, 1990-2019: a systematic analysis of the Global Burden of Disease Study 2019

BACKGROUND: Communicable disease control has long been a focus of global health policy. There have been substantial reductions in the burden and mortality of communicable diseases among children younger than 5 years, but we know less about this burden in older children and adolescents, and it is unclear whether current programmes and policies remain aligned with targets for intervention. This knowledge is especially important for policy and programmes in the context of the COVID-19 pandemic. We aimed to use the Global Burden of Disease (GBD) Study 2019 to systematically characterise the burden of communicable diseases across childhood and adolescence. METHODS: In this systematic analysis of the GBD study from 1990 to 2019, all communicable diseases and their manifestations as modelled within GBD 2019 were included, categorised as 16 subgroups of common diseases or presentations. Data were reported for absolute count, prevalence, and incidence across measures of cause-specific mortality (deaths and years of life lost), disability (years lived with disability [YLDs]), and disease burden (disability-adjusted life-years [DALYs]) for children and adolescents aged 0-24 years. Data were reported across the Socio-demographic Index (SDI) and across time (1990-2019), and for 204 countries and territories. For HIV, we reported the mortality-to-incidence ratio (MIR) as a measure of health system performance. FINDINGS: In 2019, there were 3·0 million deaths and 30·0 million years of healthy life lost to disability (as measured by YLDs), corresponding to 288·4 million DALYs from communicable diseases among children and adolescents globally (57·3% of total communicable disease burden across all ages). Over time, there has been a shift in communicable disease burden from young children to older children and adolescents (largely driven by the considerable reductions in children younger than 5 years and slower progress elsewhere), although children younger than 5 years still accounted for most of the communicable disease burden in 2019. Disease burden and mortality were predominantly in low-SDI settings, with high and high-middle SDI settings also having an appreciable burden of communicable disease morbidity (4·0 million YLDs in 2019 alone). Three cause groups (enteric infections, lower-respiratory-tract infections, and malaria) accounted for 59·8% of the global communicable disease burden in children and adolescents, with tuberculosis and HIV both emerging as important causes during adolescence. HIV was the only cause for which disease burden increased over time, particularly in children and adolescents older than 5 years, and especially in females. Excess MIRs for HIV were observed for males aged 15-19 years in low-SDI settings. INTERPRETATION: Our analysis supports continued policy focus on enteric infections and lower-respiratory-tract infections, with orientation to children younger than 5 years in settings of low socioeconomic development. However, efforts should also be targeted to other conditions, particularly HIV, given its increased burden in older children and adolescents. Older children and adolescents also experience a large burden of communicable disease, further highlighting the need for efforts to extend beyond the first 5 years of life. Our analysis also identified substantial morbidity caused by communicable diseases affecting child and adolescent health across the world. FUNDING: The Australian National Health and Medical Research Council Centre for Research Excellence for Driving Investment in Global Adolescent Health and the Bill & Melinda Gates Foundation

Global, regional, and national sex differences in the global burden of tuberculosis by HIV status, 1990–2019: results from the Global Burden of Disease Study 2019

Background Tuberculosis is a major contributor to the global burden of disease, causing more than a million deaths annually. Given an emphasis on equity in access to diagnosis and treatment of tuberculosis in global health targets, evaluations of differences in tuberculosis burden by sex are crucial. We aimed to assess the levels and trends of the global burden of tuberculosis, with an emphasis on investigating differences in sex by HIV status for 204 countries and territories from 1990 to 2019. Methods We used a Bayesian hierarchical Cause of Death Ensemble model (CODEm) platform to analyse 21 505 site-years of vital registration data, 705 site-years of verbal autopsy data, 825 site-years of sample-based vital registration data, and 680 site-years of mortality surveillance data to estimate mortality due to tuberculosis among HIV-negative individuals. We used a population attributable fraction approach to estimate mortality related to HIV and tuberculosis coinfection. A compartmental meta-regression tool (DisMod-MR 2.1) was then used to synthesise all available data sources, including prevalence surveys, annual case notifications, population-based tuberculin surveys, and tuberculosis cause-specific mortality, to produce estimates of incidence, prevalence, and mortality that were internally consistent. We further estimated the fraction of tuberculosis mortality that is attributable to independent effects of risk factors, including smoking, alcohol use, and diabetes, for HIV-negative individuals. For individuals with HIV and tuberculosis coinfection, we assessed mortality attributable to HIV risk factors including unsafe sex, intimate partner violence (only estimated among females), and injection drug use. We present 95% uncertainty intervals for all estimates. Findings Globally, in 2019, among HIV-negative individuals, there were 1.18 million (95% uncertainty interval 1.08-1.29) deaths due to tuberculosis and 8.50 million (7.45-9.73) incident cases of tuberculosis. Among HIV-positive individuals, there were 217 000 (153 000-279 000) deaths due to tuberculosis and 1.15 million (1.01-1.32) incident cases in 2019. More deaths and incident cases occurred in males than in females among HIV-negative individuals globally in 2019, with 342 000 (234 000-425 000) more deaths and 1.01 million (0.82-1.23) more incident cases in males than in females. Among HIV-positive individuals, 6250 (1820-11 400) more deaths and 81 100 (63 300-100 000) more incident cases occurred among females than among males in 2019. Age-standardised mortality rates among HIV-negative males were more than two times greater in 105 countries and age-standardised incidence rates were more than 1.5 times greater in 74 countries than among HIV-negative females in 2019. The fraction of global tuberculosis deaths among HIV-negative individuals attributable to alcohol use, smoking, and diabetes was 4.27 (3.69-5.02), 6.17 (5.48-7.02), and 1.17 (1.07-1.28) times higher, respectively, among males than among females in 2019. Among individuals with HIV and tuberculosis coinfection, the fraction of mortality attributable to injection drug use was 2.23 (2.03-2.44) times greater among males than females, whereas the fraction due to unsafe sex was 1.06 (1.05-1.08) times greater among females than males. Interpretation As countries refine national tuberculosis programmes and strategies to end the tuberculosis epidemic, the excess burden experienced by males is important. Interventions are needed to actively communicate, especially to men, the importance of early diagnosis and treatment. These interventions should occur in parallel with efforts to minimise excess HIV burden among women in the highest HIV burden countries that are contributing to excess HIV and tuberculosis coinfection burden for females. Placing a focus on tuberculosis burden among HIV-negative males and HIV and tuberculosis coinfection among females might help to diminish the overall burden of tuberculosis. This strategy will be crucial in reaching both equity and burden targets outlined by global health milestone

Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019

Background Sustainable Development Goal 3.2 has targeted elimination of preventable child mortality, reduction of neonatal death to less than 12 per 1000 livebirths, and reduction of death of children younger than 5 years to less than 25 per 1000 livebirths, for each country by 2030. To understand current rates, recent trends, and potential trajectories of child mortality for the next decade, we present the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 findings for all-cause mortality and cause-specific mortality in children younger than 5 years of age, with multiple scenarios for child mortality in 2030 that include the consideration of potential effects of COVID-19, and a novel framework for quantifying optimal child survival. Methods We completed all-cause mortality and cause-specific mortality analyses from 204 countries and territories for detailed age groups separately, with aggregated mortality probabilities per 1000 livebirths computed for neonatal mortality rate (NMR) and under-5 mortality rate (USMR). Scenarios for 2030 represent different potential trajectories, notably including potential effects of the COVID-19 pandemic and the potential impact of improvements preferentially targeting neonatal survival. Optimal child survival metrics were developed by age, sex, and cause of death across all GBD location-years. The first metric is a global optimum and is based on the lowest observed mortality, and the second is a survival potential frontier that is based on stochastic frontier analysis of observed mortality and Healthcare Access and Quality Index. Findings Global U5MR decreased from 71.2 deaths per 1000 livebirths (95% uncertainty interval WI] 68.3-74-0) in 2000 to 37.1 (33.2-41.7) in 2019 while global NMR correspondingly declined more slowly from 28.0 deaths per 1000 live births (26.8-29-5) in 2000 to 17.9 (16.3-19-8) in 2019. In 2019,136 (67%) of 204 countries had a USMR at or below the SDG 3.2 threshold and 133 (65%) had an NMR at or below the SDG 3.2 threshold, and the reference scenario suggests that by 2030,154 (75%) of all countries could meet the U5MR targets, and 139 (68%) could meet the NMR targets. Deaths of children younger than 5 years totalled 9.65 million (95% UI 9.05-10.30) in 2000 and 5.05 million (4.27-6.02) in 2019, with the neonatal fraction of these deaths increasing from 39% (3.76 million 95% UI 3.53-4.021) in 2000 to 48% (2.42 million; 2.06-2.86) in 2019. NMR and U5MR were generally higher in males than in females, although there was no statistically significant difference at the global level. Neonatal disorders remained the leading cause of death in children younger than 5 years in 2019, followed by lower respiratory infections, diarrhoeal diseases, congenital birth defects, and malaria. The global optimum analysis suggests NMR could be reduced to as low as 0.80 (95% UI 0.71-0.86) deaths per 1000 livebirths and U5MR to 1.44 (95% UI 1-27-1.58) deaths per 1000 livebirths, and in 2019, there were as many as 1.87 million (95% UI 1-35-2.58; 37% 95% UI 32-43]) of 5.05 million more deaths of children younger than 5 years than the survival potential frontier. Interpretation Global child mortality declined by almost half between 2000 and 2019, but progress remains slower in neonates and 65 (32%) of 204 countries, mostly in sub-Saharan Africa and south Asia, are not on track to meet either SDG 3.2 target by 2030. Focused improvements in perinatal and newborn care, continued and expanded delivery of essential interventions such as vaccination and infection prevention, an enhanced focus on equity, continued focus on poverty reduction and education, and investment in strengthening health systems across the development spectrum have the potential to substantially improve USMR. Given the widespread effects of COVID-19, considerable effort will be required to maintain and accelerate progress. Copyright (C) 2021 The Author(s). Published by Elsevier Ltd

Erratum to: FUGE: A joint meta-heuristic approach to cloud job scheduling algorithm using fuzzy theory and a genetic method[Cluster Comput DOI: 10.1007/s10586-014-0420-x]

Job scheduling is one of the most important research problems in distributed systems, particularly cloud environments/computing. The dynamic and heterogeneous nature of resources in such distributed systems makes optimum job scheduling a non-trivial task. Maximal resource utilization in cloud computing demands/necessitates an algo-rithm that allocates resources to jobs with optimal execu-tion time and cost. The critical issue for job scheduling is assigning jobs to the most suitable resources, considering user preferences and requirements. In this paper, we present a hybrid approach called FUGE that is based on fuzzy theory and a genetic algorithm (GA) that aims to perform optimal load balancing considering execution time and cost. We modify the standard genetic algorithm (SGA) and use fuzzy theory to devise a fuzzy-based steady-state GA in order to improve SGA performance in term of makespan. In details, the FUGE algorithm assigns jobs to resources by considering virtual machine (VM) processing speed, VM memory, VM bandwidth, and the job lengths. We mathematically prove ouroptimization problem which is convex with well-known analytical conditions (specifically, Karush–Kuhn–Tucker conditions). We compare the performance of our approach to several other cloud scheduling models. The results of the experiments show the efficiency of the FUGE approach in terms of execution time, execution cost, and average degree of imbalance

FUGE: A joint meta-heuristic approach to cloud job scheduling algorithm using fuzzy theory and a genetic method

Job scheduling is one of the most important research problems in distributed systems, particularly cloud environments/computing. The dynamic and heterogeneous nature of resources in such distributed systems makes optimum job scheduling a non-trivial task. Maximal resource utilization in cloud computing demands/necessitates an algorithm that allocates resources to jobs with optimal execution time and cost. The critical issue for job scheduling is assigning jobs to the most suitable resources, considering user preferences and requirements. In this paper, we present a hybrid approach called FUGE that is based on fuzzy theory and a genetic algorithm (GA) that aims to perform optimal load balancing considering execution time and cost. We modify the standard genetic algorithm (SGA) and use fuzzy theory to devise a fuzzy-based steady-state GA in order to improve SGA performance in term of makespan. In details, the FUGE algorithm assigns jobs to resources by considering virtual machine (VM) processing speed, VM memory, VM bandwidth, and the job lengths. We mathematically prove our optimization problem which is convex with well-known analytical conditions (specifically, Karush–Kuhn–Tucker conditions). We compare the performance of our approach to several other cloud scheduling models. The results of the experiments show the efficiency of the FUGE approach in terms of execution time, execution cost, and average degree of imbalance

Investigating the Association of Cord Blood Resistin and Birth Weight in Term and Preterm Neonates

BackgroundResistin is reported as an antagonistic hormone of insulin and in the literature. Nowadays, importance of resistin is being more highlighted in the metabolism of mother and fetus during pregnancy. This study aimed to assess the level of resistin in the umbilical cord and blood sugar at birth and evaluate the association of resistin and neonatal birth weight.Materials and MethodsThis case-control study included 80 term and 80 preterm neonates. 5ml blood sample for measurement of resistin and glucose was obtained from cord blood. Neonatal birth weight was measured by standard method. Association of resistin and neonatal birth weight was evaluated.ResultsCord blood resistin was 27.1 ± 32.2 and 21.9±9.8 ng/ml in preterm and term neonates, respectively. There was not a significant differences between Resistin and birth weight (P>0.05). Blood sugar was 78.1 ± 23.6 and 79.5±19.8 mg/dl in preterm and term neonates, respectively. Cord blood Resistin and blood sugar did not differ in term and preterm neonates (P =0.158 and P= 0.165, respectively).ConclusionThe present study did not reveal any significant differences in resistin level between the term and preterm neonates. Blood glucose was nearly the same in both groups, and resistin did not show any significant correlation with birth weight